Free Download Kinetics for Bioscientist e-book PDF
This book starts off by discussing the basics of kinetics, using
everyday examples. It then moves on to describing kinetics in
mathematical terms. Special chapters in this book are dedicated to cases
relevant for Bioscientists, e.g. zero, first and second order kinetics.
In the last part of the book, the focus is on more complex applications
of kinetics, e.g. steady-state reactions and the kinetics of
equilibria. An important aspect is to provide relevant examples and
model calculations. Every theoretical approach is underpinned by
several model calculations of real-life examples.
Content
1. Why a Bioscientist should care about kinetics
1.1 Introduction and learning outcomes
1.2 Problem: Elimination of alcohol from the body
1.3 Problem: Growth of an E.coli culture
1.4 Problem: Cancer
1.5 Summary
2. Rates, speeds and velocities
2.1 Introduction and learning outcomes
2.2 Definitions
2.3 Average and instantaneous rates
2.4 Working with instantaneous rates
2.5 Summary
3. Zero Order Reactions
3.1 Introduction and learning outcomes
3.2 Some definitions for zero order reactions
3.3 Developing the tools for a zero order reaction
3.4 Problem: Elimination of a drug from the metabolism
3.5 Problem: Transport of growth hormone receptor to cell membrane
3.6 Which equation should I use to calculate the product of a reaction?
3.7 Problem solving strategies
3.8 Equations for zero order reactions
3.9 More practice questions
4. First order reaction
4.1 Introduction and learning outcomes
4.2 Some definitions for first order reactions
4.3 Developing the tools for a first order reaction
4.4 Problem: Elimination of a drug from the metabolism
4.5 Problem: Radioactive decay
4.6 Problem: Degradation of a receptor/ligand dimer
4.7 Problem: Growth of a population
4.8 Problem Solving Strategies
4.9 Equations for a first order reaction
4.10 More practice questions
5. Second order reaction – a special case
5.1 Introduction and learning outcomes
5.2 Some general definitions of a second order reaction
5.3 Developing the tools for a second order reaction
5.4 Problem: Dimerization of the receptor for a growth hormone
5.5 Problem: Formation of active reverse transcriptase dimers
5.6 Problem solving strategies
5.7 Equations for second order reactions in which the reactants are the same chemical
5.8 More practice questions
6. Second order reaction with different reactants
6.1 Introduction and learning outcomes
6.2 Extension of the second order rate concept
6.3 Pseudo-orders
6.4 Problem: Hydrolysis of Acetylcholine
6.5 Problem solving strategies
7. Determine the order of a reaction
7.1 Introduction and learning outcomes
7.2 The significance of ‘initial rates’
7.3 Effect of reactant concentrations on rates
7.4 Equations for the determination of rate orders
7.5 Problem: Determine the rate order of a reaction
7.6 Rate orders and Molecularity of a reaction
7.7 Fractal and negative rate orders
7.8 Problem Solving Strategy
7.9 More practice questions
8. Complex reactions with several reactants
8.1 Introduction and learning outcomes
8.2 The general rate law expression for reactions with several reactants
8.3 Determining individual rate orders from experimental data
8.4 Determine the rate constant for a reactions with several reactants
8.5 Problem: Calculate rates and concentrations of reactants from data sets
8.6 Problem Solving Strategy
8.7 More practice questions
9. Coupled reactions
9.1 Introduction and learning outcomes
9.2 The General Mass Action (GMA) representation for complex reactions
9.3 The GMA representation for a reversible reaction
9.4 Problem: Calculate the equilibrium constant of a complex reversible reaction
9.5 Problem: Calculating equilibrium concentrations from rate constants
9.6 Problem solving strategies
9.7 More problem questions
10. Model Answers to practice questions
10.1 Answers to Chapter 3
10.2 Answers to Chapter 4
10.3 Answers to Chapter 5
10.4 Answers to Chapter 7
10.5 Answers to Chapter 8
10.6 Answers to Chapter 9
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